Adenylate Kinase 2 anticorps (N-Term)
Aperçu rapide pour Adenylate Kinase 2 anticorps (N-Term) (ABIN2782460)
Antigène
Voir toutes Adenylate Kinase 2 (AK2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against AK2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human AK2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 239 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Adenylate Kinase 2 (AK2)
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Autre désignation
- AK2
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Sujet
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Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates, this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: ADK2, AK 2
Protein Interaction Partner: HUWE1, UBC, MDM2, BAG3, ABCC5, ABCC6, TUFM, SAFB, MRPL12, IDH1, DSP, DLD, RAVER1, TELO2, CUL3, SHBG, SUMO2, MEPCE,
Protein Size: 239 -
Poids moléculaire
- 26 kDa
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ID gène
- 204
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NCBI Accession
- NM_001625, NP_001616
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UniProt
- P54819
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Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
Antigène
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